I have been struggling with Temporal Arteritis (GCA) for 14 months now. I had a biopsy done 1 week after I had seen my PCP for severe temporal pain. She started me on high doses of Prednisone. Referred me to a surgeon and a Rheumatologist. By the time the biopsy was done the result was negative. The surgeon warned me that we could get a false negative because I had been on the high dose of prednisone for 6 days and by the time we did the biopsy the pain/inflammation had gone away. I have had 3 relapses in 14 months. We tried Actemra along with prednisone . After 4 weeks on that I ended up with diverticulitis so we had to stop that medication. Then we tried Methotrexate along with prednisone. The side affects with that were not good. I had no energy, more stomach aches than normal and I would fall asleep in the afternoon. Very uncommon for me as I usually have a lot of energy. We had to stop that one. once stopped, all my energy came back, thank the good lord. I just had my 3rd relapse. We are now trying Rinvoq along with the prednisone. The hope for me is that we can get down to a low dose of prednisone while taking the Rinvoq. My biggest fear is loosing my eye sight so I will keep trying whatever I can in order to save my eye sight. If your biopsy is positive for GCA or if it comes out as a false negative, you might want to see about working with a Rheumatologist. My Rheumatologist has been great. He has been working really hard with me to try to find some other medication other than a steroid to get this under control and hopefully in remission. I wish you good luck with your biopsy. I do hope you get some answers from it. Please feel free to reach out and share your information. You are the first person I have seen comment on GCA on this site so I felt I needed to send you a response. This is the first time I have ever sent a response. It is nice to know we are not alone in this challenge. Please let me know what you find out. Sending prayers your way.