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I am a 74 year old female. I was diagnosed with Osteopenia in August 2024. I was seeking relief from 8 years of increasing lower back pain at Mayo. I met with an endocrinologist via zoom who recommended Evenity. When I finally met with a “Staff” surgeon in January 2025 he said I would benefit from spinal fusion, but needed to get 6 shots of Evenity prior to surgery. In September 2026 the surgery was done. I will have a loooong recovery, but the pain has subsided by a lot. Now working with physical therapy on hips and balance. Since I live in CA, Mayo hands off this time to my doctor here. He is a general practitioner, but very knowledgeable on Endo. He has had me doing this test C Telopeptide monthly, but has never explained what it is for/what he learns from it! My reading this month was 598. Does anyone know what that means? Good? Bad?
Thanks in advance to anyone that can help me understand 🙂
Marianne

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Replies to "I am a 74 year old female. I was diagnosed with Osteopenia in August 2024. I..."

@mariannegr Put it in AI. It explains it better than any doctor.

@mariannegr Are you working with an endocrinologist? A CTX of 598 indicates a high level of bone breakdown. Evenity increases both bone resorption and building but a bisphosphonate is recommended after cessation of treatment as one’s body tends to go into a period of higher bone breakdown.

For reference, I just completed twelve months of Evenity and my CTX is 102, indicating that my body has a low level of bone resorption going on. I will be getting an infusion of Reclast soon to keep my CTX low. If I don’t do this, my body will ramp up bone resorption as this is a natural process that occurs after a period of bone building.

@mariannegr Measures collagen fragments released into the blood when bone is broken down, aiding in the diagnosis of high-turnover bone diseases and monitoring treatment efficacy. I would say this is on the higher side. I would also ask for a P1NP which would tell you how active your bone building cells are.
I do this test every 3 months.