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Recurrent tumor after BCG: Was Docetaxel added to Gemcitabine for you?
Bladder Cancer | Last Active: Apr 23 12:12pm | Replies (8)Comment receiving replies
Gem/doc treatment was pioneered at the Univ of Iowa and has been shown to give as good if not better than BCG results. Gemcitabine and Docetaxel work synergistically. i.e. they complement each other and work in different ways to attack the tumor(s). I've just had my third of 12 maintenance treatments after having had 5 weeks introductory period, after which I was declared "in remission" as there was no trace of cancer. It's a little time-consuming as each chemo which is instilled sequentially, has you lying for an hour. I have had few if any side-effects.
Some light reading for you:
https://medicineiowa.org/spring-2023/bladder-cancer-breakthrough.
Good luck.
Replies to "Gem/doc treatment was pioneered at the Univ of Iowa and has been shown to give as..."
@gemdoc25 I am set for a third TURBT on May 8th and will then begin a course of 12 BCG treatments. I had six BCG treatments in 2024, and three Adstiladrin treatments in 2025 - 2026. I now have high grade pT1. I am highly alergic to Mitomycin (found out the hard way) and am interested in Gemcitabine (delivered as Inlexzo), or Gem-Doce, but concerned that it is a chemotherapy drug that may - or may not -share properties or actions with Mitomycin that I could not tolerate. Any information on reactions to Gemcitabine or Gem-Doc, particularly neurotoxicity?
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@gemdoc25
Thanks much for this information. Will be discussing with my physician.