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What does "lock in the gains" really mean?
Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (6)Comment receiving replies
My understanding with taking Forteo is that both the osteoblasts and osteoclasts are increased while on the med. When I stop, the osteoblast boost will stop but it takes a lot longer for the osteoclast boost to stop. This would lead the bone to break down faster for awhile. But with taking something like Fosamax which slows down the osteoclast activity, you would slow any bone loss till the effect of the Forteo is done. I guess this might take a year but I don't think they are entirely sure on the length of time needed.
Again, this is just my understanding of what I've read though 🙂
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@luckypup Thank you so much for sharing your understanding. That is what I had understood, too -- that the osteoclast activity takes awhile to slow down, so you need to take something (eg a bisphosphonate) to stop the breakdown. But somewhere along the line I read -- or saw a diagram -- showing that that elevated breakdown normalizes within a few months. So that is why it seemed odd to me that I would have to take the hated (!) Fosamax for two whole years!! I'll have to find that study or diagram. If I do, I can share it.