I realize this string is a year+ old, but maybe someone has a perspective: my large prostate (114 cc) is limiting my treatment choices. Could I have Holep or Aquablation or another treatment to REDUCE my prostate size in order to expand my PCa treatment options? Right now, what I'm being told is RP or hormones/ADT for several months and then, possibly, radiation. Neither of those is attractive. I'm 80, in good health otherwise, TC1, 4+3, localized PCa, no metastases showed on recent PSMA-PET. Anybody have similar issues and dealt with the PCa in 2 steps?