← Return to Bone turnover markers (CTX and P1NP): do you have a baseline?

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Profile picture for mayblin @mayblin

@gracie7 you are on the right path... being proactive about your diet, supplements if necessary, exercise and fall prevention is the foundation of management; more importantly, questioning the right drug of choice to start the treatment journey.

Have you had a DXA scan and a FRAX/FRAXPlus risk assessment?

@gently had a great post re bone turnover markers.

Regarding the Prolia recommendation: it's an antiresorptive (slow down bone breakdown) that carries a unique "rebound" risk if stopped. It essentially requires a lifetime commitment or a carefully planned transition to another antiresorptive (a strong bisphosphonate), which adds significant long term complexity. It also complicates future treatment sequencing in the event you need any bone builders. Because of this, it's often not the first line choice -especially when anabolics (bone builders such as Forteo or Tymlos) have shown in several studies to be very effective for corticosteroids induced osteoporosis. Discussing with your doctors about the right drug to start is absolutely crucial, as your instinct tells you.

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Replies to "@gracie7 you are on the right path... being proactive about your diet, supplements if necessary, exercise..."

@mayblin, Thank you! It seems I can't get enough information and you all are wonderful.
I wonder if me now being totally off prednisone, not drinking sodas or taking supplements that I now read increase osteoclast activity and forcing myself to eat much more protein might make a difference in the result??? Along with exercise and weights of course. Best - Gracie

@mayblin, oh sorry, I forgot to answer you. I did have a DXA scan and it showed I was osteopenia everywhere except the left hip which was -2.8. I think the REM scan was more accurate as one outlier of the -2.8 showed an inaccurate result....unfortunately. Thanks - Gracie