@surftohealth88 Thanks for that article. Really provides an answer to my question about the clinical value of uPSA tests. As is usually the case, there is no one-size-fits-all approach to surveilling for a recurrence. My old urologist, who retired, used to say, ‘The data aren’t the problem, it’s how people use the data’. Wise words.

Interesting that the article questioned the use of 0.2 as the PSA value for defining biochemical recurrence. They advocated for a lower value given that uPSA could detect the trajectories toward a BCR at PSA values < 0.1. My salvage RT was initiated when my PSA was 0.11. None of my docs suggested waiting for my PSA to rise higher. Of course, the presence of a palpable nodule in my prostatic fossa that glowed like a Christmas tree on the PSMA PET scan weighed heavily in moving forward with treatment.

Anyway, thanks. I’m seeing the bigger picture for the use of uPSA testing now.