@synthiame The mycophenolate was prescribed to suppress the immune system, which is attacking and destroying the insulation (myelin sheath) around the autonomic and peripheral nerves. The hope is that it will slow the destructive process. It may, but not necessarily, have the added benefit of allowing some recovery. In my case the primary symptoms were numbness, tingling, hyper sensitivity, and shooting (electric-shock-like) pains in the feet and toes, as well as orthostatic hypotension (drop in blood pressure when standing). I've been on the mycophenolate for about 18 months. The shooting pain is noticeably less frequent, sensitivity to touch is a little less, and other symptoms of peripheral neuropathy are about the same. I'll be tested again at Mayo in June and find out if the orthostatic hypotension has changed.