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Rut Roh Rorge - PSA wrong direction

Prostate Cancer | Last Active: 2 days ago | Replies (20)

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Profile picture for Jeff Marchi @jeffmarc

@mjp0512
You did have quite a few aggressive issues along with the Gleason nine. Really disappointed to hear somebody has Become CRPC so quickly after having both ADT and Nubeqa. That really Blows up the theory that being on an ARP can really delay castrate resistance.

I think this may come down to something that Richard Wassersug PhD has said about being on the drugs and having prostate cancer. He contains that cosmic rays Are causing the castrate resistance, We are getting hit by them constantly. Your having so many aggressive issues would lead to a lot of cell growth which then could be hit by cosmic rays and become resistant.

I’ve been around six years since I became Crpc. It doesn’t mean things are almost over. Continuing treatment can make a major difference and new drugs are coming out all the time.

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Replies to "@mjp0512 You did have quite a few aggressive issues along with the Gleason nine. Really disappointed..."

@jeffmarc - Heck Jeff, cosmic rays make as much sense as anything else at this point. Maybe the CDx will shed light on some strange mut causing the short timeline to CRPC. My concern now is how much the PET is going to light up.

@jeffmarc We exist on this planet bathed in cosmic rays 24/7 and always have and always will.
If he is going to blame this factor in our environment for becoming castrate resistant, you might as well blame it for every cancer there is.
I’ve read the articles/comments you’ve posted by him and they are quite informative about the role of ADT and how it relates to CRPCa, but his cosmic ray theory is a bridge too far for me.
Cosmic rays can cause mutations in anything and everything, depending on their intensity so it almost seems superfluous to bring it up.
I mean, millions of men do NOT become CRPCa, yet they are bombarded by these same cosmic rays so I can’t see his reasoning at all on this.
I think it comes down to the individual, their particular cancer genetics, and their immune system…ie, some will - and some won’t. Just my take from what I’ve gleaned from the literature. Best,
Phil