@bajjerfan I know about niacinamide as I've been taking it for several years. I found a company that makes an extended-release form and the flushing is minimal. I've began taking it to help regulate my blood pressure, not for its effect on cholesterol. It may be why my cholesterol levels have never been in the "high" range, they've always been in the low to middle of the "borderline high" range. This latest combo that I'm taking now has gotten my numbers down 25 points to what is considered "near optimal". A lot of my problem was mostly with the "good" HDL cholesterol being too low. It's because I wasn't getting a lot of exercise when I was still working at a stressful 9-5 desk job. Now that I'm retired, I'm getting more regular exercise, which has helped raise my HDL. But I'm still working on that.