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Letrozole later onset side effects

Breast Cancer | Last Active: 20 hours ago | Replies (29)

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Profile picture for prarysky @prarysky

@louisewalters I also had a Zometa infusion in October 2025. My PA initially ordered another infusion 6 months later but I've postponed that until I meet again with my endocrinologist.

Did your oncologist tell you why s/he recommends the Zometa every 3 months for 2 years? I think it is prescribed when cancer is found in the bones, but wonder if they are recommending this schedule to prevent it from developing in your bones. I'm going to ask my oncologist this question at my next visit.

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Replies to "@louisewalters I also had a Zometa infusion in October 2025. My PA initially ordered another infusion..."

@prarysky When I was initially diagnosed the oncologist told me she didn’t want the cancer to spread or come back and was going to throw everything at me. My understanding with Zometa is that because the letrozole can cause osteoporosis and is hard on our bones, we are given Zometa to prevent that from happening. However, Zometa also has very scary side effects if you google it. All of these drugs are so hard on us! I am in Canada and I wonder if treatments vary country by country. Best wishes!