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@jlharsh sorry for not connecting for a while but life has been busy! I’ve been having some adverse health issues the past few weeks and couldn’t quite figure out what’s ailing me. I’ve not been feeling myself now for the last 3 months and wasn’t sure if it’s heart related, seasonal related or what. I’ve been lacking energy and drive for activities I normally find joy and purpose in. Long story short I saw my general practitioner and they started with blood tests and checked for anemia, thyroid and some of the “low hanging fruit.”They also checked for negative effects from the statin. The results came back with my CK and albumin score being very high! They’ve decided to have me take a 2 week break from the rosuvastatin and take another blood test at the end of the two weeks to see if my levels drop back to normal. All I know is that I’ve felt very bad and that overwhelming wave of fatigue and muscles “screaming” for oxygen! @jlharsh I remember you said that you couldn’t tolerate any statins and are taking some sort of shot every month. Could you refresh my memory and an up to date regimen of what’s working for you? I know you went to a lipid specialist at mayo for guidance.

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Replies to "@jlharsh sorry for not connecting for a while but life has been busy! I’ve been having..."

No worries, @dlkreps. I absolutely understand how time goes by trying to get through poor energy/health challenging times. Finding joy in daily life sounds like an extreme struggle right now and I am glad to hear you are partnering with your general practitioner to figure out why.

I recently learned it takes some time for improvement if statins are the culprit, so it is a good thing you are taking the step now to stop taking rosuvastatin. It is also important to address potential heart and kidney problems in addition to muscles.

The injection that works well for me in Inclisiran (Leqvio). Starting requires an initial shot, then a 2nd in three months, a 3rd in another three months. It is every 6 months after that. I am scheduled for my 7th injection in a couple of weeks.

My cardiologist is at Mayo Clinic MN. He has considerable focus on prevention and their Statin Intolerance Program. From this program they will coordinate with other departments as needed, a tremendous benefit of Mayo Clinic’s integrative approach to improving patient health. I also listened to a recent continuing education podcast with him as a guest discussing statin myopathy (including so much more). From our discussions I think you may find it super valuable.

- Dr Kopecky, Mayo Clinic MN
https://www.mayoclinic.org/biographies/kopecky-stephen-l-m-d/bio-20054286
- Statin Intolerance Clinic MN
https://www.mayoclinic.org/departments-centers/statin-intolerance-service/overview/ovc-20442137
- Mayo Clinic Cardiology Continuing Medical Education Podcast: Statin Myopathy

I absolutely recommend contacting Dr. Kopecky or Statin Intolerance Clinic for guidance. You can pursue an appointment here: http://mayocl.in/1mtmR63

I relate to your experience and would like to continue hearing about your experience. This comment has general information and I am certainly happy to share more as you have questions.

What dose of rosuvastatin have you been taking? You mentioned discontinuing. Are you changing anything else in the meantime, other medications, diet, exercise, etc? Are you experiencing symptoms other than muscles, and has your doctor discussed potential heart or kidney concerns?