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Share Your Brain Tumor type & Years since Diagnosis

Brain Tumor | Last Active: 21 hours ago | Replies (102)

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Profile picture for Jeff & Rea @jeffpaeste

Jeff was diagnosed with Grade 4 glioblastoma (GBM), IDH-wildtype and MGMT-unmethylated, in December 2025. The tumor was identified after he suffered a grand mal seizure on December 21, 2025. Prior to this, he was in excellent health and maintained a very active lifestyle. Following the seizure, he was hospitalized for 24 days, including 11 days in the ICU.

His tumor is considered inoperable. Following his diagnosis, he experienced significant left-side weakness that affected his strength, mobility, and balance. His short-term memory, cognitive function, and vision were also impacted. Through 7 weeks of physical and occupational therapy, along with 5 weeks of cognitive therapy, he has made meaningful progress. He is stronger now, his movement has improved, and his memory and cognitive abilities continue to get better.

He completed 30 sessions of radiation and chemotherapy (TMZ) on April 8, 2026. We will be traveling to the Mayo Clinic to explore additional treatment options, and he is expected to begin Optune Gio with TMZ in May. I am also in communication with two clinical trials and praying he will qualify.

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Replies to "Jeff was diagnosed with Grade 4 glioblastoma (GBM), IDH-wildtype and MGMT-unmethylated, in December 2025. The tumor..."

@jeffpaeste what clinical trials are you hoping to get into? Only asking because I’ve been diagnosed with GBM gone through surgery to remove the tumor then 3 days later had emergency surgery to stop a brain bleed and to remove more of the tumor, 40 rounds of radiation while taking TMZ and 6 rounds of high dose TMZ. Now on the GIO wearing it everyday over 90% of the time.