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Urologist said I could stop Orgovyx. Your thoughts?
Prostate Cancer | Last Active: 4 hours ago | Replies (37)Comment receiving replies
Been off Orgovyx now for a week after being on it for 20 months. Last test results a month ago were PSA less than 0.04 and testosterone less than 1. Hoping for a good future.
Replies to "Been off Orgovyx now for a week after being on it for 20 months. Last test..."
@johnny8924
Here’s some information on how quickly your testosterone could come back
In the HERO study, relugolix demonstrated sustained testosterone suppression superior to that of leuprolide acetate (97% vs 89%; difference 7.9% [95% confidence interval, 4.1–12%; p < 0.001]).
Men (N = 934) were randomized (2:1) to receive relugolix 120 mg orally daily or leuprolide acetate injections every 12 wk for 48 wk.
Overall, 74 of the 137 men in the relugolix cohort recovered to testosterone >280 ng/dl, with a median time to recovery of 86.0 d (95% CI, 65.0–92.0), versus two of the 47 men in the leuprolide cohort, with a median time to recovery of 112.0 d
https://www.sciencedirect.com/science/article/pii/S2588931123002900
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@johnny8924 Good luck. With longer ADT and higher age testosterone recovery is extended so even from Orgovyx it can be 3 months or longer. You will probably have a PSA bounce when your testosterone recovers since you are 1 year out from IMRT and cancer cells take up to 2 years to die.