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Rising PSA at 5 months post-RALP

Prostate Cancer | Last Active: 34 minutes ago | Replies (27)

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Profile picture for wheel1 @wheel1

There are two schools of thought in the Oncology world developing for beginning treatment on BCR. One is PSA driven by reaching the established 2.0 PSA considered BCR threshold. The other emerging is the image driven treatment determined by it being seen on the PSMA-PET. This would typically exceed the PSA 2.0 level before being seen. The arguments include better focusing of radiation and results showing no detrimental effects on outcome. Similar to the studies that show awaiting initial treatment beginning up to six months post cancer diagnosis to determine what you are going to do has shown no overall change in outcomes. I think though that you might set your own upper PSA number if something is not showing on the PET that you pull the trigger. Clearly that number is what everyone wants to figure out. Definitely consult and you are in 2nd opinion territory again before deciding your course.

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Replies to "There are two schools of thought in the Oncology world developing for beginning treatment on BCR...."

@wheel1

This patient had RP , so his BCR is definitive at PSA 0.2 , not 2.0.

@animate , I am so sorry that you have to deal with this : ((, my husband is in similar situation, his PSA is slowly rising and it is tremendously stressful.

I can totally understand your fear about PSA rising to almost 0.2 and doctors still taking their time to act and do all tests but is it always like that : (((. That is why we did uPSA every single month (on our cost) so we would not be "surprised" *sigh.

Try to insist on things moving faster, call every day to check for cancellations etc.

Wishing you all the best and may RT completely and forever eradicate your cancer 🍀

@wheel1 Thank you for your comment. I understand that you meant the 0.20 PSA value. I guess I still need to identify the PSA trend and rate of change to determine the urgency to begin treatment.