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Vitamin K: High Doses of MK-4 and MK-7 Show Promising Results
Osteoporosis & Bone Health | Last Active: 2 hours ago | Replies (46)Comment receiving replies
@ccps101 Most of the people here haven't rushed. We are on this site to research, learn, and compare notes and perspectives with others, including yourself.
As one example, I have spent several months reading about Vitamin K MK4 and have looked at about 28 sources from research papers and doctor's interviews. As an outcome I am only this week starting to take only 1/3 of the Japanese protocol while continuing to research.
As a second example, @kathleen1314 has shared many research links about taking Strontium which I and others have read carefully. Some have decided to take Strontium supplements, and others (including me) to not take strontium, after reading those and considering their current person situation.
Again, I appreciate your perspective and suggestions around diet!
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@kfhoz I was in the process of pulling together some material about MK-4 for my cardiologist who specializes in cancer (mine is breast cancer). At my recent visit, I asked her if she thought it would be okay for me to take MK-4 since I am on Eliquis, one of the newer blood thinners known as DOACs (direct acting oral anticoagulants). Since I have a history of atrial fib, I have ruled out MK-7 because some people report heart palpitations. My cardiologist/oncologist said she didn't know anything about MK-4 but would pass my information on to the pharmacist affiliated with the hospital.
I am impressed by your research of so many sources! Your decision to start with 1/3 of the Japanese recommended dosage for MK-4 is exactly the one I have in mind. The following article is one that supports my decision about using a lower dose:
Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis
Key takeaway:
"In postmenopausal women with osteoporotic fractures, supplementation with either 5 or 45 mg/day of MK-4 reduces ucOC to concentrations typical of healthy, pre-menopausal women.
https://pubmed.ncbi.nlm.nih.gov/30816822/;