@dks2500 Hi. BCG has been used for 40 years and they call it the gold standard. My first urologist (local) tested me for biomarkers that would cause failure. That test showed only a 40% chance of success. The local urologist said they were still going to start treatment with BCG. I had TURBT recently at Mayo and the surgeon told me that not enough research has been done on biomarkers to validate that testing. Good luck. Hope this info helps you.