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New type of test for PSA: Prostate Screening EpiSwitch (PSE) test
Prostate Cancer | Last Active: Apr 15 10:15pm | Replies (26)Comment receiving replies
Thanks, this is very helpful additional insight @gently
I agree with your view that getting a range(grid) over just a positive/negative would be helpful.
I have a number of positive indicators like PSA, PSA trend and density and ISOpsa pointing to additional investigation, versus a negative MRI which based on this forum is not sufficient to avoid biopsy. I am scheduled for a second MRI and I am considering EPIswitch to potentially delay/eliminate the biopsy per your and Jeff's guidance.
I am very interested to connect with Mayo, but unfortunately they have eliminated virtual consults as a first contact. So cost would be a flight + hotel + consult to consult on my numbers and whether the biopsy is needed. Based on my reading of the research and forums it would be unlikely to avoid the biopsy without a more conclusive negative indicator like Episwitch.
Thanks for your thoughts, I hope I am negative too!
Replies to "Thanks, this is very helpful additional insight @gently I agree with your view that getting a..."
skimore, you could get a second opinion closer to home. You have a better grip on this than I
had/have. Episwitch is easy.
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@skimore If no PIRADs identified in MRI either bad MRI / MRI reading or no significant cancer. A PIRADs of 2 is non-cancerous over 85% of the time; PIRADs 3 over 75%. Did not mention how much over 6 the ISOpsa was, but that is the breakpoint so if 6.x still fuzzy. If concerned get the Episwitch PSE since they will give you a yes or no for biopsy. It would be better if there was a gradient, but most genetic tests are "black boxes" so not unusual. A negative biopsy even random is considered definitive and eliminates the "medical necessity" of the PSE.