@dks2500 We were not told of this possibility at Mayo Clinic where my husband had his initial diagnosis and surgery. Perhaps this testing is newer or just not widely accepted yet? I had not heard of it. But then when my husband went onto Keytruda, I asked the urologist about tumor testing for p51 levels to see if that therapy had good odds of working, and he said they "Don't do that". It was strange because I had just had tumor testing for my SCC starting Libtayo which works on the same pathway as Keytruda, but he blew it off. Perhaps the difference in having a urologist manage cancer treatment vs an oncologist manage care?