@elm123 You are fortunate to have access to a neurologist affiliated with a medical school! “Confused and anxious” is very understandable. No alcohol is showing a difference for you! That is very interesting. My husband has a glass of wine most nights…maybe discontinuing that would help! And there is probably no way to know if that is making the difference for you, or if the infusion of b1 is…I hope you’ll update us here…Best wishes to you and your husband!