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Making sense of pre-treatment bone turnover markers
Osteoporosis & Bone Health | Last Active: 2 days ago | Replies (3)Comment receiving replies
Not sure what information you already have. So here goes.
CTX is bone Resorption you want that number to be lower and P1NP is bone Formation you want that number to be higher. The best way to use this data it to understand if a treatment path is working or not. Depending on the type of treatment the numbers are affected differently.
Here are my baseline bone markers (before treatment) and my most recent March results.
CTX (Resorption) Baseline = 385
P1NP (Formation) Baseline = 45.5
March Result
CTX = 295
P1NP = 29.5
Because I am using BHRT it has a antiresorptive effect on the bone makers. So my CTX would be lower due to less bone resorption occurring and P1NP would also be lower because of less bone building needed with less resorption happening.
These results are telling me that my treatment path is working at this time and has stabilized my bone loss.
Bone Markers are just one of the pieces in the puzzle. Your Doctor should be able to help better interpret you numbers.
Replies to "Not sure what information you already have. So here goes. CTX is bone Resorption you want..."
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@oknowwhatpixie Thank you! This is all so confusing for me and I'm just trying to understand it. When I looked at my bone markers it looked bad to me so I wasn't sure why the lab didn't flag it as concerning....maybe it's because it's "normal" to lose bone as we age. Is your only treatment BHRT? It sure looks like it's working for you! I'd like to get that myself since I'm only 59, but my doctors are all scared to give it to me!