Hi @skd4953 and welcome to Mayo Clinic Connect! Feeling like you’ve been hit by a truck after 10 days of Rosuvastatin (Crestor) is not fun. It is a good thing you have made this connection so you address it.

I have tried darn near every cholesterol drug and absolutely understand what you are feeling. I cannot tell you if/when your side effects will subside. That is a question to ask your doctor sooner than later. I do have a couple thoughts that have helped me.

When I suspected drug side effects my prescribing doctor told me to draw a stick figure and indicate where my pain was. I quit the med, wrote the date on the picture and threw it in a drawer. After 30 days I drew another stick figure. Then, I compared the two pictures and told my doctor what I learned. He confirmed I was having side effects and were able to move on together.

Another thought is to ask about reducing how much Crestor you currently take. There are different types of statins and they are not equal. Rosuvastatin is a good one, though one that may be a good idea to take the lowest dose possible only two times per week. Crestor is a drug with a longer half-life so at least some will stay in your body all the time even by reducing the frequency it is taken. This provides full benefits of the drug.

Is this the first statin you have tried? Do you think you will talk to your doctor?

Hi thanks for your advice. I’m going to stop taking the Crestor
I’d like to some more natural options. Red yeast rice for example, so I’m researching. In addition to the body aches, I have migraines, have vertigo and I have two tendon issues in my shoulder, all can be problems using Crestor. I spoke to my doctor and let him know what I’m looking into.

I too started Rosuvastatin, or Coreg, about 1.5 weeks ago, only 5 mg. since I'm sensitive to drugs. I started getting achy legs at about 1 week. Initially I figured it's due to my PT exercises I'm doing for a hamstring injury, but it's both legs all the way up & down in the muscles, especially upon rising from sitting. I think I'll do what Janell suggested & notify my cardiac doc. Adjusting the dose to not every day may be an option. I'd tried 10 mg of Lipitor before & it was much worse pain, had to go off. I do need to get those LDL numbers down.

Thanks, Patty

@skd4953 Why are you on a statin? Are your lipid levels really high or just borderline? Were you placed on a statin because of your age? I had borderline high lipid levels but the ratios were acceptable but the PCP wanted me to be on a statin because of my age--77. I tried it for about 3 or 4 days and I hated it! I switched to OTC methods and my levels dropped by 20%. I take Red Yeast Rice daily and Garlic tablets. Also push the fiber to keep things moving through. I have NO side effects and I am not feeding big pharma with the costly drugs they promote. Ask around and do some research.