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scbil avatar

PADCEV + KEYTRUDA: results and side effects

Bladder Cancer | Last Active: 2 days ago | Replies (21)

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Profile picture for Lisa, Volunteer Mentor @lls8000

@scbil, From reading some of the posts about this combination of treatments under the Bladder Cancer group, it sounds like it can be quite effective for the right person. But not everyone will be able to tolerate each type of treatment. There are people here with stories of adverse reactions from Keytruda for a primary lung cancer, but there are many success stories too. How did the appointment go today? Will she be continuing with the Keytruda/Padcev combination?

This discussion regarding Starting Keytruda may be helpful, if she is continuing with the treatment: https://connect.mayoclinic.org/discussion/starting-immunotherapy-keytruda/

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Replies to "@scbil, From reading some of the posts about this combination of treatments under the Bladder Cancer..."

@lls8000 thanks for this note. Some really interesting information and pro/con testimonial comments. We didn’t make our appointment with the oncologist as my wife was just released from six days in the hospital for nausea, diarrhea and inability to eat anything without a gagging response. She was simply too weak to meet with her Dr. today. This is her second hospitalization in a row following the treatments and subsequent significant tests and procedures each time without any definitive results. A new treatment series starts this Wednesday so I’m anxious and concerned to see how the reaction is this time. Thank you again for the information and links. I will have my wife review them all this week.

@lls8000 thanks for the reminder to post out results. Scan and oncology meeting went very well. Lung nodules reduced 50% and no new growth noted in the bladder cancer. A real blessing and answer to prayers. Due to my wife’s immune system being “beat up” and her hospitalization following the last two treatment cycles, it was decided to give her a treatment of Keytruda but no PADCEV this past Wednesday and then take a cycle break from treatments. Focus is on her improving her ability to taste/eat/and keep her food down for the next 2 weeks and then restart Keytruda without PADCEV until her next scan later in May. She is still dealing with all the after effects of the treatments but we are encouraged and thankful for the recent results. Staying positive with good medical treatment and care and a prayer army.