@charlesgreenberg I was on Verzenio but could not keep it down. At $8,400 a month throwing it up was not acceptable. Now on Kisqali and still getting use to it. I was on Anastrozole and had wild mental swings. Now on Letrozole. Trying to manage and get the right mix is a full time job. I am very honest with my care team - which are wonderful. I find that the medication can be more difficult than active treatment. Best wishes.