@kjoed53 and all... Thank you for your kind words. This isn't a journey for the timid or the weak. Through the years, I developed the ability to insist on questions heard, answered and a partnership with my doctors and others. No more sweet Southern lady stuff... I now have a steel backbone, slightly crooked and with a few cracks and bruises now, but steel and holding up just fine. Acceptance of the situation once it was logically and fully determined was my key to moving forward. It took a lot of quiet, deep, meditative thought and prayer to begin to accept this body and make careful, thoughtful personal decisions. I am in control. Not my wonderful doctor. nor the PA nor nor family... I am in control and work well with my supporters.

I pray you get solid answers from medical personnel you trust and admire. Then. move forward to the best for you! blessings, Elizabeth

@kjoed53 have you tried splitting your dose.?

@kjoed53 Please stay on 25mg until the pain is gone, not mostly gone. I also have anemia of an unknown cause that returns every time I get off of prednisone. Have you researched if prednisone messes with your Free Kappa Lt Chains? I use my AI engine for this type question. Prednisone messes with anything it finds - it does not understand MYOB protocol

When I was first Dx with PMR I saw three hematologist, one retried on me. I had a bone marrow biopsy early on. The last one told me the problems were "in my blood not with my blood". Meaning the bone marrow was good, manufacturing was good. That is what the hematologist is concerned with. Your blood picks up trash throughout your system and your liver and kidneys clean it out. I wish you a good visit with your hematologist.