In mid Canada the city of Winnipeg, Manitoba (north of North Dakota) has an excellent highly respected clinic doing Arthrosamid injections at $4000 Canadian ($2900 US) per knee. ---- Pam Am Clinic, 75 Poseidon Bay, Winnipeg. I have been a client for 30 years, top notch specialists. Haven't tried the new injections, still only doing cortisone for two arthritic knees. Determined to not have TKR. Love the gym and biking, walking not so much but can shop. Ran for 50 years. Like many here not sure of the efficacy of Arthrosamid. Hyaluronic injections were no better than cortisone for me at $750 C per shot.