BIRADS 5 AND 155.0 cc prostate

@floridaman I was in the same situation as you with the size and mri results. I had the decipher done on the biopsy which came back .34 low risk. My urologist recommended a simple robotic prostatectomy which remove 101 grams of prostate around my urethra so I would pee again. That worked Great ! He didn’t recommend a radical prostate removal because of it’s size would cause a lot of blood and diapers for ever I have one tumor in the prostate, no where else He recommended active surveillance. Year later this past Jan 2026, I had a PSMA. Came back negative! Also I forgot to mention my pathology report on the biopsy a year ago gave it a 4+3=7. Which is opposite of a decipher .34 !! I may ask for the slides to be read by John Hopkins. I hear that 1 out of 2 come back down graded from what the original pathologists reported. I’ve heard that due to liability, that many are upgraded from some pathologists teams Right now I am going to talk to my urologist about IGRT radiation. Heard that it can be cured! And I want to live longer than SS believes I will 😂. I listen to PCRI on YouTube Very good experts

May I recommend 2 resources:

Patrick Walsh's book "Surviving Prostate Cancer"

Prostate Cancer Foundation cpf.org Patient Guides free for download or hardcopy.

Best wishes

There's a lot to learn initially about prostate cancer. When it came to visit me I was fortunate to find a great resource. I highly recommend a visit to PCRI.org. This website has a wealth of information which is easily understandable, accurate, and state of the art. Give it a visit and see if it can be of educational assistance to you. Best of luck going forward.

@mikefassino
Rather than send your slides to John Hopkins for review, you should consider having them reviewed by Dr. Epstein. He is a real expert in analyzing Prostate cancer slides. He does charge $500 for the review, but you can call him and speak to him for quite a while about all the details of your biopsy. A lot of people who have used him.

Dr. Epstein biopsy
https://advanceduropathology.com
He will contact the place you had the biopsy and arrange for everything to be done. You don’t have to be involved with that.

@mikefassino
Rather than send your slides to John Hopkins for review, you should consider having them reviewed by Dr. Epstein. He is a real expert in analyzing Prostate cancer slides. He does charge $500 for the review, but you can call him and speak to him for quite a while about all the details of your biopsy. A lot of people who have used him.

Dr. Epstein biopsy
https://advanceduropathology.com
He will contact the place you had the biopsy and arrange for everything to be done. You don’t have to be involved with that.

@jeffmarc Info only (sample of one, me). I filled out the online form for Dr Epstein review and never heard back from them (nor did I get any confirmation email so possibly I did something wrong. I could/should have called them (xxx-760-2037) as well but did not so that's on my for not following up.

@floridaman I do not think they take insurance, it's out of pocket and paid 'up front' from my understanding. In your case (4+3) it might be worth it - if he comes back with 3+3 that would be a good change. My biopsy was 4+4 so there would be less chance of a big change for me.