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Rituximab or Remicade for Rheumatoid Arthritis RA

Autoimmune Diseases | Last Active: Apr 24 11:50am | Replies (28)

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Profile picture for judyresnick @judyresnick

My daughter has 5 auto immune diseases and she is still searching for the right drug for herself. She is on long term use of steroids, and they need to get her down to a low dose as it is destroying other parts of her. She took Remicade. She had a terrible allergic reaction while they were infusing. She started bleeding and unfortunately the doctor persisted that they finish the dose. It was really, really bad. But, she hasn't tolerated any of the newer drugs, but Humira worked well for her for years. It's well tolerated, and it's one of the oldest of. its class, so more time and research. If. that's a choice, I recommend asking your doctor. I think insurance covers it. For her, it stopped working, but it worked for a long time.. and she is really bad. Good luck. I am only on here because she won't and I am searching for her too. With 5, you can imagine Lupus, Crohns RA, Bechets, shorgrans.

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Replies to "My daughter has 5 auto immune diseases and she is still searching for the right drug..."

@judyresnick

I was on Humira for 4 months and it worked for me. Since I have scleroderma with arthritis and GI involvement, now Rituximab is one of my next options. I still think Humira is a better choice. It is no longer covered by insurance due to multiple biosimilars of the same class available at lower cost. I am trying to get it approved.
I have seen other responses with allergic reaction to Remicade. It is good to know.
It is unfortunate that your daughter cannot take Rinvoq - an oral drug with multiple indications similar to Humira.
There are also multiple clinical trials ongoing with CAR-T therapy in Lupus. Those treatments are known for neurotoxicity, but some oncology patients (where CAR-T has been used for years) report very positive results.
https://www.cartautoimmune.com/what-to-expect-from-car-t-cell-therapy
Many thanks for sharing your experience.