My endocrinologist at first recommended Reclast which I refused and now Tymlos which I’m still extremely concerned about. I have rheumatoid arthritis and have read nothing but horrible side effects from these medications. I cannot take the oral ones due to GERD. I don’t want to take any of them. I’ve no history of fractures and I am terrified of the long lasting side effects of pain and problems on top of my RA problems. I don’t know what to do. Anyone else choose not to take osteoporosis drugs and regret it later?

I started Tymlos back in January after a lot of back-and-forth with myself and honestly I relate so much to what you’re saying because while I know it’s supposed to help long-term bone health, the day-to-day reality has been rough with those random palpitations that make you pause and wonder if something’s wrong, that weird leg weakness and muscle pain that comes and goes just enough to be annoying but not predictable, and on top of that trying to stay consistent with a daily injection schedule while traveling (especially across time zones) feels almost unrealistic like you’re supposed to be enjoying your trip but instead you’re thinking about when to stab yourself and whether you’ll feel off afterward and it kind of builds this quiet resentment toward the whole process where even if you understand the benefits, you still end up thinking “I really don’t like doing this every single day,” so yeah, just wanted to say you’re definitely not alone in feeling that mix of frustration, inconsistency, and just plain dislike for the treatment even when you’re trying your best to stick with it.

@gravity3

Thank you, I will.

Hello. I started Tymlos 2 weeks ago. I was pretty healthy and fit before that. In fact why I have 3 vertebra fractures compression and deterioration all the way up and down and extreme thinning in the hips is a bit of a mystery to everyone so far. I have experienced some of the usual side effects and sometimes think I'm trying out an experimental drug with potentially murderous side effects. But here is what I do know 100%: My spine will continue to deteriorate which will be quite painful and possibly put me in a wheelchair. Or 10%: I will get bone cancer from Tymlos. So my choice includes all the known discomforts, giving up my precious Pinot Noir, and just one more pain in the ass thing to do while traveling, but I think back on my Mother living on Tramadol like a drug addict, making excuses to get her fix early till thankfully at 94, the Covid did her in, and I feel I have to muscle through the next two years anyway I can. Naive or stupid, what's the verdict out there?

P.S. I'm going to post this in the Osteoporosis group too so I can get a bigger cross section of thrashing or support.

I’ve been on Tymlos now for over two years. Good results especially in my spine on my DEXA scan. There’s no more warning for bone cancer after two years that has changed now so you can be on it for a long time. I only take a half a dose every day because I I am petite… And was experiencing too many side effects from a whole dose