Initially my Alk Phos was in the too high range and now it's considered too low, I've been on exemestane for 3 years. Both my liver and kidney values are always way off since being on the treatments for my breast cancer. As lesliek mentioned, my dr never seems to care, even when the values seem very bad. They only ever care when my ANC goes to 0.8 or lower, nothing else ever gets mentioned. My PCP gets concerned about all of it but oncology never cares.