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Trying to decide on treanment

Prostate Cancer | Last Active: 27 minutes ago | Replies (16)

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Profile picture for brianjarvis @brianjarvis

Much of this decision should be about what you’re telling them you want, rather than what options they’re telling you to choose from.

(I also had a 7(4+3), so we had the same options available. I had 28 sessions of proton radiation + 6 months of ADT + SpaceOAR Vue. Being retired, working those 28 days into my schedule wasn’t a problem.)

You should ask yourself —> What are you looking for with your choice of treatment? What do you want? What don’t you want? What are the characteristics of each component of treatment being offered that gets you to where you want to be? What have you told them your preferences are?

Why choose to be in a trial? If one of your priorities is successful treatment, what certain value does being in a trial bring you?

What questions have you asked them so far that had led you to still be undecided?

For the "adaptive" IMRT, is that “90% success rate 10 years out” the average or the best/worst?

Are you using SpaceOAR Hydrogel or SpaceOAR Vue?

The short course of proton SBRT may increase the risk of urinary bother, given the higher dose each fraction. Dr. Rossi has a lot of information about proton in his portion of this 2023 Mid-Year PCRI presentation: https://www.youtube.com/live/WTqPnSRYtW4

—> Starting at 3:38:45

His comments about Proton SBRT start at about 4:30:45.

I wouldn’t leave it up to a coin flip. I’d make an affirmative choice on the one I preferred, because it’s a decision - the most important decision in my life - that I’d have to live with for the rest of my life.
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Just to be sure: your MRI report made no mention of seminal vesicle invasion or perineural invasion, and your biopsy report made no mention of cribriform pattern, or intraductal carcinoma.

At 68y, was this your first PSA test? If not, what was your PSA Doubling Time?

Have you had a Biomarker (genomic) test and a Genetic (germline & somatic) test?

Some of those answers may help you decide.

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Replies to "Much of this decision should be about what you’re telling them you want, rather than what..."

@brianjarvis
When my brother had five sessions of SBRT to treat his cancer, he did have urinary issues. Flomax resolved them and they only went on for a month or two.

Just got a call from a friend of his yesterday who is Having 20 sessions of IMRT. He said after the third session, he felt a lot of burning when he was peeing, and it was driving him nuts. He tried AZO and it did not help. I think cystitis is a common problem for people that have around 20 sessions of IMRT. We’ve heard many people in this forum, complain about cystitis issues. I know from personal experience that having close to 40 sessions, with the lower radiation, doesn’t seem to cause a big problem with Cystitis, in comparison.