One of the struggles I have with this is trying to determine how helpful continuing to take Letrozole is for me with ILC. I have an early stage ER+, PR-, HER2- cancer, Stage 2, detected by a 5mm mass. But after lumpectomy, there were two other tiny masses that never showed up on mammogram or MRI. Negative lymph node. I was also treated with radiation. The Predict tool is based on ductal carcinoma, or, at best, all breast cancers lumped together. At 72, the Predict tools predicts very very little advantage from using an AI, and I'm definitely not liking the symptoms from Letrozole, or it's risk to my bones. I already have severe osteoporosis. But I suspect the Predict tool underestimates the impact of an AI for ILC vs ductal cancer. Size of the tumor is a variable in the Predict tool, but what is the real size of our tumors when they're stringy, and multiple locations and "hiding?" Does anyone else have thoughts about the effectiveness of AIs for us?