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Aromatase Inhibitors: How to choose and manage side effects?
Breast Cancer | Last Active: 16 hours ago | Replies (96)Comment receiving replies
I am stalling. Diagnosed in September 2024. Haven’t tried any yet and doing a lot of research. A question to AI (artificial intelligence) says the Aromasin/exemestane might be the most tolerated but there are lots of comments here about the quality of the manufacture of each drug, generic or brand. I will be discussing with my pcp and a pharmacist. Also, a new drug called giredestrant was submitted to FDA for approval and ruling is expected on December 18, 2026. It supposedly has a higher rate of efficacy and lower rate of discontinuation. I will probably try one before December rolls around.
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@ladydinana okay as an update, I need to read my post more carefully! I was diagnosed in September of 2025, not 2024. Did discuss with my PCP and pharmacist, who said Anastrozole was best tolerated but does have bone density loss issues. I’m walking with weighted vest and a video I watched said some impact movements are even more helpful than walking and weight training (which I’m also doing as my son is a physical trainer). My doc had said she liked the non steroidal ones over exemestane which was steroidal, even though it has less impact on bone loss. I had some achiness on Anastrozole, stopped for a week and restarted and it’s fine now so I’m hopeful. Will check bone density again in about six months to check. Good luck to us all!!