I read the research and the NEW research substantiates women taking BHRT in later years. (as long as they take prometrium with the estrogen). The tests have been ongoing now for 30 years and they are finding it is not a concern like once thought. I see a doctor at UCSD who tests my levels and we discuss cancer risks vs. cancer protections vs. my family history of cancer. I am using it to support the bones. I have had one Reclast and on my second year of Tymlos. My bone increase was modest so the BHRT was important for me to try to see if I can boost the numbers.