Time will tell with HRT and its use after decade plus of menopause. Sure sounds like a good plan for osteoporosis., we sure need better pharma options! That being said, my gynecologist said absolutely not for me...mom had breast cancer, 2 years later ovarian cancer. We did the BRAC testing to see if breast cancer could be genetic; it wasn't. We were told by the genetic counselors that our risk (my sister and I) was the same as the general population, but yet to be vigilant to any breast issues and to get regular mammograms, which of course we have been. BTW when I asked endo about it, he had me ask the gyne, I don't think he prescribes it for any osteo patients.