I am 85 and have total body osteoarthritis but the calf pain really is not related to that. The first calf pain I had was during directed exercise to strengthen my legs. Later my left foot looked very strange to me but the doctor did not see anything abnormal. Ultra sound was done and nothing was discovered. A couple of years later I underwent an angiogram to find that the artery on my left leg is almost totally blocked with plaque. The pain in that leg comes from a variety of things: PAD, atherosclerosis, peripheral neuropathy and more recently lymphedema. I hope your pain does not indicate any of that and I wonder if years ago had I had a premonition of this dilemma I could have done anything differently.