@blueberre Hi. I applaud you for starting HRT. I began the estrogen patch at 69 yrs old (2 months ago). I have osteoporosis (3.1 in one area). No fractures . I had a complete hysterectomy in my late 40’s, which contributed to my bone lost. Plus I am small boned woman. Since they now removed the black box warning, I decided to get on the patch. My dose is 0.25, which I understand is a low dose but all that’s needed to protect the bones. I understand the patch is safer (from oral), because it bypasses the liver. I do not have breast cancer in the family. My reason for starting the patch, for me it’s much safer and peer effective than any current osteoporosis treatment. I’m not willing to deal with those side effects of the osteoporosis meds. I’ll try this treatment first. I figure I much rather take a chance on breast cancer then to have those terrible side effects of the osteoporosis meds/shots. I also weight lift and jog everyday. Eat as healthy as possible. I understand it might take 2yrs to show up in DEXA scan, but every day on the patch I figure is one day closer to being stronger.