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My results after 1 year of Evenity
Osteoporosis & Bone Health | Last Active: Apr 4 11:42am | Replies (93)Comment receiving replies
@marytlemons
I just had my first injection of Evenity three weeks ago. I am 75 and have been very reluctant to try any drugs, but my numbers have been quite low. I, too, have experienced extreme fatigue on Evenity, which is not even listed as a side effect. I can sleep for 10 hours at night and still feel extreme fatigue when I wake up in the morning. Then, throughout the day, I get headaches and fatigue off and on, usually late in the afternoon, for which I have to lie down. I told my doctor about this and she said "that is not a usual side effect". Well, it seems like we are not all alike.
I have also had some gut issues. And this is only my first dose. I might have to discontinue the Evenity because the fatigue is almost unbearable. I have been very active my whole life, walked to grade school, high school and all over in college. I have remained very active up until this age. I think no matter how active a person is, osteoporosis is just sometimes inevitable.
Please let me know if anyone else has suffered the extreme fatigue like I have.
thanks
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@pam52 If you can hang on for 3 months you should get the majority of the benefit from Evenity/romosozumab. It sounds very difficult, but given that you have started consider the below information as part of your decision.
See this OsteoBoston interview with a doctor who is an osteoporosis specialist. The chart with the romosozumab (brand name Evenity) action over time starts at about 34 minutes in, but I suggest also listening to the whole interview.
Excerpt from transcript at about 34:21
" ...look at these are markers of bone turnover look for example at P1NP. This tells you how quickly bone is being formed. Someone on Romosozumab [Evenity] gets a big stimulation of bone formation but it's transient. It stops after about three months. [Romosozumab] also actually reduces bone resorption. CTX is a marker of bone resorption. So [this drug] does exactly what combination therapy does but it does so with one drug. It increases bone density more than Forteo, more than Fosamax, and it decreases the risk of fracture more."