@jnmy & @cholash Wow, predisposition is a great question, one I have been thinking about lately.
Here is a recent paper (I'm reading it now) on just that issue -
https://www.frontiersin.org/journals/tuberculosis/articles/10.3389/ftubr.2025.1735568/full
Do you want to read it too and discuss further (looks lots of good reference studies linked to it)?