@leeosteo 1. I assume you are an older person . If your cac score is zero then it is likely you are not generating soft plaque or you would have calcification by now. Of course that could change. 2 Statins do nothing to lower your LPa and there is even a few small studies that show it might increase it. There are some new drugs that do and more in the pipeline. Also vitamin b3 (niacin) can lower it modestly but it has annoying side effects.