Hi @denise134 and @rb991

I had severe side effects on capcetamine.

My oncologist switched me from 2 weeks on/1 off at a similar dose as denise134, to 1 week on/1 week at 1000mg.

Then we stretched treatment out for a year instead of 6 months.

It made a big difference and I was able to finish the treatment.

This was after several other chemos and radiation and such, so if capcetamine is your only line of defense I can see the docs not wanting to reduce too much, but worth an ask.

Hope this helps, hugs to you both.