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Pleomorphic xanthoastrocytoma tumor (Pxa): help
Brain Tumor | Last Active: Dec 9, 2023 | Replies (132)Comment receiving replies
do you have some thoughts on immunotherapy options for a PXA tumor with features of an anaplastic astrocytoma?
our oncologist wants to switch over to a BRaf inhibitor. two other patients with this same, unusual tumor have had success switching to a combination of two bRaf inhibitors. but we know that there are serious side effects, so we're holding off as long as humanly possible. we also know that is the only other option we have from Penn.
Over a 10-year battle with this cancer. Many operations and chemo treatments due to multiple resurgences. virtually maxed out on lifetime radiation treatments.
Replies to "do you have some thoughts on immunotherapy options for a PXA tumor with features of an..."
I'm so sorry to learn about your battle with this cancer, @minnniceguy. I thought you might be interested in reading this journal article about the successful use of BRAF inhibitors in oncology: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977279/
Here's some information about three main BRAF inhibitors Vemurafenib, Dabrafenib, Sorafenib:
– https://www.mayoclinic.org/drugs-supplements/vemurafenib-oral-route/description/drg-20075147
– https://www.mayoclinic.org/drugs-supplements/dabrafenib-oral-route/description/drg-20061178
– https://www.mayoclinic.org/drugs-supplements/sorafenib-oral-route/description/drg-20068145
I'd also like to introduce you to @audrapopp @meg4434 @ecdhope @daniellemarie, who've shared their or their loved ones experiences with these targeted therapies. @minnniceguy, could you share more about the side effects that concern you the most?
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Hi. I hope your daughter overcomes the tumor. Today there are great advances with the new treatments. In the blog of xantoastrocitoma you can find various information.
I wish the best for you