Tylenol is processed thru your liver. I once heard an emergency room Dr that said Tylenol was the leading cause of liver transplants in this country today.

@joefriday49 ditto!

@joefriday49 Tylenol is something more like a placebo for me. Dang it. I have a maximum dose of 1500mg a day, which is only three capsules. If I need to take it, I keep it at two. I am on peritoneal dialysis everyday, and my eGFR [corrected for dialysis] is about 13%. The true eGFR is a lot lower.

Recently, because I cannot have general anesthesia for knee and hip issues, here is my go-to pain relief program: Arnica gel for topical use, or arnica montana tablets for bruising/inflammation, with success. I have also used a generic Diclofenac sodium topical gel. Yes, this is an NSAID, but it is topical and will not theoretically be processed by my kidneys. Truthfully, I figure I am already on dialysis for life, so why not make myself comfortable!? Another thing I have added at times, not on any regular basis, is CBD/THC tincture, at night.
Ginger