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TAKE CHARGE of your prostate cancer and future - ASK QUESTIONS
Prostate Cancer | Last Active: Apr 1 6:07pm | Replies (23)Comment receiving replies
A study at Memorial Sloan Kettering Cancer Center, of 2664 men who were diagnosed with GG1, indicated that 76% were still on AS after 5 years, 64% after 10 years and 58% after 15 years.
The amazing thing is that only two men were deemed to have a disease that could have been cured on immediate treatment. The risk of distant metastasis was 0.6% at 10 years.
Some GG1 men will think they want treatment because they’re concerned with the possibility of being one of the 2 out of 2664 who developed metastasis after 10 years.
I wonder if this study had been properly explained to those diagnosed with GG1, who chose immediate treatment, ended up putting themselves at unnecessary risk for negative treatment side effects by submitting to immediate treatment.
This is the contention of Dr. Matt Cooperberg of UCSF.
The other interesting thing is that 25% of those that go off AS have no “trigger” reason….probably just anxiety…
https://pmc.ncbi.nlm.nih.gov/articles/PMC7480884/
Replies to "@jeffmarc A study at Memorial Sloan Kettering Cancer Center, of 2664 men who were diagnosed with..."
@handera Excellent article. The authors do, however, emphasize that this cohort was considered ‘very low risk’ to begin with.
Originally they started with over 2900 men and so approximately 300 were already too far gone to be included in the study.
I think earlier, more aggressive screening is the key to all this and that has to start with education from a young age.
Women are encouraged to seek breast exams and have mammographies done at a younger age if there is a family history; men need to get that same advice - and LISTEN TO IT!
Phil
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@handera
The 50% figure that I mentioned came from talks or videos I’ve seen, that covered active surveillance.
It might be in that Dr. Klotz or Epstein videos as well. I would not doubt the MSK numbers, but it may not be what’s been found everywhere.
Here is a video with Dr. Laurence Klotz, one of the experts on active surveillance.
Here is a video by Dr. Epstein discussing active surveillance and more