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Wife's Diagnosis SCLC- Chemo Next Week-What Should I Do?

Lung Cancer | Last Active: May 18 1:36pm | Replies (55)

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Update and question. Back in August 2025 my wife was fighting a rash and itching from her first immunotherapy treatment (Imfimzi). After getting the rash emilinated, the doctors decided to not continue that treatment.
Then in early January the cancer returned and had spreaded, The doctors then started her on a different immunotherapy treatment, Tarlatamab (Imdelltra). At first she was tolerating this very well and seemed to be improving.
But about 10 days ago her sense of taste completely changed. Now everything she drinks tastes like salt water.
This has caused her to have trouble with fatigue and balance problems. The doctors gave her a hydration IV yesterday and today she is better. And she has another IV scheduled Friday.
We are trying everything the dotors and our family can think of to fight this. She sips cherry kool aid now.
The doctors suggested trying zinc supplements ands eating cantaloupe, Just starting those today.
Just wondering if anyone else has had anything like this and what might have helped.

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Replies to "Update and question. Back in August 2025 my wife was fighting a rash and itching from..."

@mimicmckay, did you end up starting Tarlatamab? Have you experienced taste side effects? Anything similar to @bovic21's wife (see above)?

@bovic21 Sounds like me with my chemo. Could barely get water down. My first cycle I put a small amount of 7 up in my water and it helped. Didn’t help this cycle. I’ve also put lemon, which helps a little. My dietician suggested cucumbers in water but ai didn’t have any. I haven’t tried koolaid. I will speak with dietician again today and see if any new ideas. I sympathize with your wife.

@bovic21 that is rough. I wonder if using a straw might help keep her hydrated?

A quick internet search suggested this product. I don't have any experience with it, but it might also be worth a try.
https://metaqil.com/