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I’ve had PMR for 4 months, and taking 20mg prednisone per day to control the pain. My doctor has put me on Methotrexate to help begin to taper down on the prednisone in a couple of months. I’ve not seen any messages dealing with Methotrexate as a treatment for PMR. Should I be worried?
Replies to "I’ve had PMR for 4 months, and taking 20mg prednisone per day to control the pain...."
Decades ago when my mother had PMR and prednisone was the only treatment I remember the health aids bringing methotrexate shots near the end of her life. She dealt with it for the last 15 years of her life.
So no, I don’t think you should be worried.
Hello @bigpapa19730, You will notice that we merged your discussion with an existing one on the same topic. If you click the link below, it will take you to the beginning of the discussion.
-- Using methotrexate with PMR: https://connect.mayoclinic.org/discussion/using-methotrexate-with-pmr/
You might also want to take a look at these related discussions:
-- New Methotrexate Study in PMR: https://connect.mayoclinic.org/discussion/new-methotrexate-study-in-pmr/
-- PMR and Methotrexate: https://connect.mayoclinic.org/discussion/pmr-and-methotrexate/
Not sure I would be worried but if I had questions I would definitely talk to my rheumatologist. What makes wonder about being worried?
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Hi bigpapa,
It was my understanding from my rheumatologist that I had to try methotrexate because medicare required it. I went from 6 months of prednisone (7/24-1/25) to methotrexate to kevzara (2week intervals tanked my WBC) to Humira (then stopped by doctor at Mayo 7/21/25) without any pain relief at all. Still Unmedicated and in severe pain. Later this month I will ask for either Actemra or back to Kevzara (at 3 week intervals). Each person reacts differently to medications. Give it a go. Praying it works for you!