@tufty For fatigue, I take SOL GOGO supplements and for clearing my body of toxins and improving immunity, I take the SOL LIVER supplements. I was told that in my case "SOL IMMUNITY" would not help what I needed-as for immunity. Last year, I was pretty bad off and was taking 4 each, 2/day. The GOGO, I could not take past noon, so I took 4 at 6 AM and 4 at noon. If I took at say 2 PM, I would not be able to sleep. I did stop taking them for a while and the fatigue crept back in. Now, I am taking 2-3 of the GOGO early in the morning and 2 at noon. When my fatigue goes away, I will back down to 1-2, 2/day. I hope this helps.