@kathleen1314 One can never extrapolate study results with strontium ranelate to the over the counter supplement that some people are taking that includes strontium citrate. This is the point that both doctors made that I agree with.
I would like to see studies done using strontium citrate at pharmacological dosages that far exceed what one would ingest through their diet, which is what people are ingesting without any evidence that it’s effective.
People are free to come to their own conclusions but we should be careful not to confirm our own bias but extrapolating data from studies on unrelated compounds.
I am well versed in scientific principles as I have two degrees in science, one of which is in microbiology. I was also a practicing registered nurse for many years. However, that doesn’t qualify me to provide advice to others on how to treat their osteoporosis. I can only share what I’ve learned and done for myself. But this is what I hold as a value for myself and others here approach this differently. I have seen people who recommend medications and supplements outright and that concerns me.
I have known about strontium for years and chose not to go down that path until there is evidence for taking strontium citrate. Others are free to form their own decisions about that and I wish them well.
There isn’t a one size fits all solution to osteoporosis and many factors play a role, as I’ve found in my case. Today I should learn whether my changed approach over the past two years has been effective as I should be getting the results from my DEXA from last week.
I haven’t fractured again after 27 months which means I have defied the odds of up to 30% of having another fracture within 2 years. This was using a pharmacological approach combined mostly with HRT, exercise (LIFTMOR-style training and other weight exercises, impact, and HIIT), and nutrition.
Depending on how well this has worked, I will continue as I am or perhaps I’ll look at other options. But I will firmly hold to using scientific evidence for my approach.
@oopsiedaisy
you say: "One can never extrapolate study results with strontium ranelate to the over the counter supplement that some people are taking that includes strontium citrate."
Answer:
Well, yes and no.
The bone-building mechanism (the way the strontium atom itself interacts with bone cells) is considered the same for both. Whether it’s attached to ranelate or citrate, the strontium ion is what actually gets incorporated into the bone matrix.
What I believe that you are saying is that these points enumerated below may change between different formulations:
1. Bioavailability; Ranelate does seem to be more bioavailable than citrate; to me that is a plus
2. Clinical Proof: As in.... there are no large clinical studies on the supplement strontium
citrate; normal for supplements, but not for what I would wish.
3. The carrier and safety in that, for example Strontium Ranelate has side effects which seem
to be attributed to the specific drug formulation. These were not found in the strontium
citrate studies. But then large scale studies may be needed to find rare side effects.
I believe that I made all the above points in my previous replies and the links to posts which I provided.
Strontium Citrate is a supplement which is regulated by the FDA as a dietary supplement; it is also available from Canada where it is regulated more stringently as a Natural Health Product (NHP) which have to be licensed and reviewed for safety and quality.
You say strontium citrate studies are needed; I agree that we need more:
Here is what we seem to have so far:
1.3 cases studies from Sara Dehart, https://strontiumforbones.blogspot.com/2018/01/in-memory-of-sara-shackleford-dehart.html
2.Mots and Comb and a study comparison: https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
3 Case studies: https://strontiumforbones.blogspot.com/2018/02/bmd-increases-by-varying-amounts-with.html
4.Moise studies: https://strontiumforbones.blogspot.com/2014/10/monitoring-bone-strontium-intake-in.html
5. Various formulations including strontium citrate, animal study: https://pmc.ncbi.nlm.nih.gov/articles/PMC11012416/
6.AlgaeCal studies: https://blog.algaecal.com/wp-content/uploads/Doctor-Info-Sheet-SB.pdf
7.AlgaeCal studies: https://www.algaecal.com/research/clinical-studies
8.Case studies: https://symbiosisonlinepublishing.com/nutritionalhealth-foodscience/nutritionalhealth-foodscience67.php
I am happy that you have found a bone regime that works for you. I celebrate your good news and would never downgrade or question what you are doing or question the research that went into your decisions or imply that you need to justify it with lists of research and information.
Indeed, I think that your decisions are about more than "you coming to your own conclusion". I think that you spent time and that you thought much about what was best for you and how to best accomplish your goal. I think that your "choice" was actually a reasoned and thoughtful decision based on good logic and information. I rejoice that it is working for you, and I appreciate you sharing it with all of us so we may learn from your experiences.
I do not think that you are " providing advice to others on how to treat their osteoporosis" or donning a mantle of qualification which you do not have. I think that you are kindly answering questions and sharing your life experiences.
I also do not think that you are "recommending medications and supplements outright" nor a certain style of training covered by a licensing model for which many pay, when you share your life choices. experiences and the reasons for which you have made those choices. I welcome your input and am thankful for the information.
Thank you.