@linnead I tapered off pred last August after being on it for over a year. I was also on Actemra infusions and continued them every 4 weeks. Soon after I went to 6 weeks with no pred. My blood markers became normalized. About 2 months ago my PMR pain returned with a vengeance, although my blood markers didn’t show it returned. Now I’m back on a short course of pred and Actemra every 4 weeks again. I feel better since I’ve restarted pred. I have a new visit with my Rheumy this week to plan the next move. The theory is that I cut back on Actemra too soon after stopping pred. I hope that’s the answer. 🙏