Problems with Sleeping on Orgovyx

Posted by rnpalarino1 @rnpalarino1, Mar 18 7:23am

I am almost 80 years old. Gleason score of 9. Prostate removed over four years ago. Biochemical recurrence after two years. Put on Orgovyx. I have been on and off the medication for over two years. I can’t have radiation because of complications from removal of my colon-I have what is called a J-Pouch. Orgovyx appears to be holding the cancer back and I don’t have many side effects. However sleeping is a problem. I have been using Ambien on and off to get a good night’s rest. Thoughts from the group please about how to get a good night sleep without using Ambien. Or should I just keep taking it periodically?

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Yes I ahve some sleep issues with Orgovyx...not as bad as early on when I first started...but between that and frequent night time urination, it is a hassle..at times..then there are periods when I sleep ok..it seems I always get off to sleep and sleep better after about 3 am to 8 am..I sometimes take a baby aspirin that helps, or Benedryl..just another side effect..got another year of Orgovyx I think..

hope you find something that works..if so let me know !

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Having problems with sleep is a common issue with people that are on ADT. Frequently it’s caused by hot flashes and night sweats Are you having those problems? If so the Embrlabs.com has a wave device that really stopped the night problems for me and. Other people, I know.

You say you’ve been on and off drugs for years does that include Orgovyx?

This problem usually does go away over time according to this article.
https://www.endocrine-abstracts.org/ea/0109/ea0109s7.3.
I am 78 and have no problem sleeping with it, but everyone is different. I’ve also been on ADT for eight years so maybe that’s a factor. In my case, hot flashes, and night sweats are over, At least at night.

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Profile picture for xahnegrey40 @xahnegrey40

Yes I ahve some sleep issues with Orgovyx...not as bad as early on when I first started...but between that and frequent night time urination, it is a hassle..at times..then there are periods when I sleep ok..it seems I always get off to sleep and sleep better after about 3 am to 8 am..I sometimes take a baby aspirin that helps, or Benedryl..just another side effect..got another year of Orgovyx I think..

hope you find something that works..if so let me know !

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@xahnegrey40
It's funny that you should mention this. It's exactly what has happened to me.
Been on Nubeqa and Orgovyx since last March. I used to be able to get to sleep within 15/20 mins of lying down. Now it seems I watch the clock for an hour/hour and a half.
When I finally get back to sleep I then need to get up to pee.
When I get back to sleep it's the best sleep after 2/3am.
In January I tested positive for Influenza A. I was using NyQuil PM and for 3 weeks slept really good.

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I've had sleep issues for a long time. Lupron and Orgovyx made it worse. I take Temazepam every night and sometimes add Trazadone to the mix and sleep well. I found ADT knocked me down some but missing a night of sleep put me into an Eeyore state the next day. Frankly, not concerned with a mild sleep drug addiction.

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I find easily available THC helps. Delta 9 is still legal.

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Profile picture for xahnegrey40 @xahnegrey40

Yes I ahve some sleep issues with Orgovyx...not as bad as early on when I first started...but between that and frequent night time urination, it is a hassle..at times..then there are periods when I sleep ok..it seems I always get off to sleep and sleep better after about 3 am to 8 am..I sometimes take a baby aspirin that helps, or Benedryl..just another side effect..got another year of Orgovyx I think..

hope you find something that works..if so let me know !

Jump to this post

@xahnegrey40

Same exact thing on my end. I'm 18 months in with Eligard. Terrible sleep before 3 am but it tends to get better afterwards. I'm not currently taking anything for it but I'll keep waiting for that one AHAAA moment! 🙂

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Hi,
I find Trazodone helps a lot, sometimes with 2 Benadryl. Zzzzzz most of the night. Still get up to urinate, but other than that I've been sleeping well. Caveat: I've only been on for a week.

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